Non-NGSS Articles

Gut Microbiota Features in Young Children With Autism Spectrum Disorder

Gut Microbiota Features in Young Children With Autism Spectrum Disorder

SUMMARY: This study sequenced bacteria flora from the fecal samples of children with autism versus healthy controls. Results showed that there was a lower amount of Bifidobacteria species and higher levels of Lactobacillus species in the autistic children. There were higher amounts of short chain fatty acids (specifically butyrate and propionate).

LESSON COMMENTS: The results of this study can be compared to the results of Comparing GI flora in autistic children to typical children. Some results are similar, such as the higher levels of Bifidobacteria and low levels of Lactobacillus; however, the amount of SCFAs differ. In this article, only butyrate and propionate were measure whereas in Comparing GI flora in autistic children to typical children, all SCFA levels were measured. What other difference are there in the graphs for each of the articles? Are the SCFAs measure with the same unit of measure? What are the differences in methodology?

Coretti, L., Paparo, L., Riccio, M. P., Amato, F., Cuomo, M., Natale, A., Borrelli, L., Corrado, G., Comegna, M., Buommino, E., Castaldo, G., Bravaccio, C., Chiariotti, L., Berni Canani, R., … Lembo, F. (2018). Gut Microbiota Features in Young Children With Autism Spectrum Disorders. Frontiers in microbiology, 9, 3146. doi:10.3389/fmicb.2018.03146