Forces & Interactions, Life Science, Physical Science, S&F 1: Cells (MS), S&P 1: Atoms & Molecules (MS), S&P 2: Investigating Electrical Force (HS), S&P 2: Synthetic Materials (MS), S&P 4: Molecule Traits (HS), Structure & Properties of Matter, Structure and Function

Using Nanoparticles to Treat Antibiotic Resistant Bacteria

Recent advances in the treatment of pathogenic infections using antibiotics and nano-drug delivery vehicles SUMMARY: This article talks about the different ways to combat antibiotic resistant bacterial infections. Most of the articles and methods focus on nanoparticles, coating nanoparticles with antibodies to detect pathogens, and creating an immune response using vaccination-like methods. LESSON COMMENTS: An… Continue reading Using Nanoparticles to Treat Antibiotic Resistant Bacteria

Life Science, S&F 1: DNA to Proteins (HS), S&F 2: Cell Function (MS), Structure and Function

Structure and Function of MCR-4

Action and mechanism of the colistin resistance enzyme MCR-4 SUMMARY: Colistin is an antibiotic that is considered to be a last resort against antibiotic resistant bacteria. Unfortunately, an enzyme called MCR-4 has evolved which makes bacteria resistant to colistin. Researchers want to understand the structure and function of MCR-4 in order to combat it. There… Continue reading Structure and Function of MCR-4

Physical Science, W 2: Digital Info (HS), W 3: Digital vs Analog (MS), W 5: Devices (HS), Waves & Electromagnetic Radiation

Using Computers to Model Antibiotic Resistance

Simulating Multilevel Dynamics of Antimicrobial Resistance in a Membrane Computer Model SUMMARY: This article uses a computer program to model how different factors contribute to the rate of antibiotic resistance in bacteria. The results aren’t predicting anything, they’re just showing the number of possibilities this program can take into account to help give a better… Continue reading Using Computers to Model Antibiotic Resistance

Inheritance & Variation of Traits, Inheritance 5: DNA Technology (MS), Life Science

Phage Therapy on Infected Graft

Phage treatment of an aortic graft infected with Pseudomonas aeruginosa SUMMARY: The first part of this article talks about using phage and antibiotics (separately and together) in vitro to reduce bacteria biofilm. Researchers found that phage alone was enough to reduce biofilm to almost zero; however, there is the concern (noted in other papers) that… Continue reading Phage Therapy on Infected Graft